Is Aleve Hard On Kidneys - HealthyKidneyClub.com (2022)

Naproxen May Damage Kidneys

How to Maintain HEALTHY KIDNEYS to Avoid Other HEALTH Problems? 7 Ways to Keep Your KIDNEY Healthy

One of the most popular NSAIDs in the pharmacy is naproxen. It was originally only available by prescription under the name Naprosyn. Now doctors can write prescriptions for naproxen as a generic pain reliever or under the brand names Anaprox, Anaprox DS, EC-Naprosyn, Naprelan and Vimovo .

Naproxen has also been available over the counter for years in products like Aleve, Aleve PM, Menstridol or Midol Extended Relief. There are also dozens of house brand naproxen products people can buy without medical supervision.

We fear that this NSAID as well as similar drugs have a long list of serious side effects that most people are either unaware of or ignore. Kidney damage is just one complication to pay attention to as this reader notes.

Why Is Advil Bad For Your Kidneys If It Is Processed By The Liver And Tylenol Not So Harmful When I

Asked
10 Jan 2014 by Twfinklea

samson2340

Advil, Excedrin, and Motrin have Ibuprofen in them. Aspirin and Ibuprofen are not good for people with kidney disease. I have Chronic Kidney Disease Stage 3, and aspirin caused me to go into Acute Renal Failure. My Nephrologist told me, NO aspirin, NO ibuprofen. Advil and Excedrin were the only thing that helped me with headaches or arthritis pain and it has been very hard for me to stick to Tylenol. You can be sure if you take too much Tylenol, it can also cause issues with the kidneys, so I take 1/2 the dose of 500 mg. Drinking lots of water has helped more than anything. Most people don’t take medication with a full glass of water. Just a sip will do they think. But to protect your body parts, use lots of water.Hope this helps.

Taking Nsaid Pain Relievers For Granted:

If you come down with a headache or your back starts to hurt, the go-to drugs of choice are nonsteroidal anti-inflammatory drugs . Millions of people rely on pain relievers like celecoxib , diclofenac , ibuprofen , meloxicam and naproxen to get through the day.

We have heard from many people in pain that they cant manage without an NSAID. Here are just a couple of comments from readers:

Angela in Portland, Oregon relies on ibuprofen:

Advil is my go-to pain reliever. I only use it when its all that will work for me. I have tried through the years to find another pain reliever. If my pain is manageable I dont take anything. I only take it when I dont have a choice. I dont know what I would do without Advil.

Michelle in Marietta, Georgia, also depends on ibuprofen:

Ive been using 800 Motrin for as long as its been available. I remember seeing a Mayo Clinic TV Special and they used it as a first try against pain. It was their go to pain reliever. It ALWAYS helps my pain. After two shoulder surgeries I took two hydrocodone pills, then only 800 Motrin. The doctor couldnt believe I wasnt taking the hydrocodone. Same with my knee replacement.

Vaudi in Fayetteville, North Carolina, loves Celebrex:

Ive taken Celebrex for years. When I had back surgery a year ago, I had to stop Celebrex for 3 months. I could barely move. I couldnt wait till the day when my spinal neurosurgeon said I could take Celebrex again. At last I had a spring in my step and felt great.

Read Also: Can You Have 4 Kidneys

Other Stories About Nsaid Pain Relievers:

Bob in Chapel Hill, NC, on NSAIDs and Kidney Damage

I had to stop regular use of naproxen because of kidney damage. I was an orthopedic surgeon for 40 years. I had to stop prescribing the NSAID butazolidin because it caused leukemia and a number of other side effects. Then I became more cautious about prescribing other NSAIDs because of the risk of heart attacks,

HW on ibuprofen:

I have had several experiences with side effects of a severe nature. A friend took Motrin for arthritis. It led to kidney failure. That led to a kidney transplant. My friend subsequently died from complications.

My husband took aspirin, then Motrin and other NSAIDS for arthritis. He developed a severe allergy that caused serum sickness. Just because these drugs are available over the counter does not mean they are harmless.

What Are The Complications Of Analgesic Nephropathy

Is Aleve Hard On Kidneys - HealthyKidneyClub.com (1)

Some cases of acute kidney failure have been linked to the use of painkillers, including aspirin, ibuprofen, and naproxen. Many of these people had risk factors, such as:

  • Lupus
  • Chronic kidney conditions
  • Recent binge-drinking alcohol

Talk with your healthcare provider for more information about diagnosis and treatment of analgesic nephropathy and kidney failure.

Read Also: Pomegranate Kidney Stones

What Are The Symptoms Of Analgesic Nephropathy

These are the most common symptoms of analgesic nephropathy:

  • Fatigue or weakness, feeling unwell
  • Blood in the urine
  • An increase in urination frequency or urgency
  • Pain in the back or flank area
  • A decrease in urine output
  • Nausea, vomiting
  • Widespread swelling
  • Easy bruising or bleeding

Some people have no symptoms. Kidney damage may be picked up by routine blood tests. The symptoms of analgesic nephropathy may look like other medical conditions or problems. Always talk with your healthcare provider for a diagnosis.

How Does Ibuprofen Or Acetaminophen Affect To Kidney

NSAIDs have important unfavorable effects on the kidney that you should know about.

Here is the science behind the issue. Ibuprofen and other NSAIDs hinder prostaglandins, and that can cause an issue due to the fact that prostaglandins dilate capillary resulting in the kidneys, according to iytmed.com. Preventing prostaglandins may result in kidney anemia and therefore severe kidney injury.

A simple blood test might show a rise in creatinine if your kidneys are being affected, typically seen within the first 3 to seven days of NSAID therapy. Severe kidney injury can occur with any NSAID though naproxen appears to be a bigger culprit. In one study, folks who took NSAIDs had twice the risk of acute kidney injury within 30 days of starting to take the NSAIDs. Good news is its reversible if you stop taking them.

In individuals with hypertension, taking NSAIDs long term may aggravate underlying hypertension. Individuals with kidney problems at baseline regularly get in difficulty with NSAIDs, however if you are taking ibuprofen for extended periods of time its not a bad idea to have a check of your kidney function with a quick blood test. Keep in mind, intense kidney injury from NSAIDs does not cause any symptoms.

Bottomline

NSAIDs are safe for the liver, but can cause a problem with kidney function that is reversible if you stop taking them. Typically safe but worth taking notice of.

Recommended Reading: Is Pomegranate Juice Good For Kidneys

Is Aspirin Safe For Regular Use

When taken as directed, regular use of aspirin does not seem to increase the risk of kidney disease in people who have normal kidney function. However, taking doses that are too large may temporarily- and possibly permanently- reduce kidney function. In people with kidney disease, aspirin may increase the tendency to bleed. People who already have reduced kidney function, or other health problems such as liver disease or severe heart failure, should not use aspirin without speaking to their doctor.

Early Detection Is Critical

A-level Biology Tricky Topics: The Kidney

People with declining kidney function typically experience no symptoms until failure is imminent. And until recently doctors had no good way to detect early signs of kidney failure. The most accurate measure required 24-hour urine collection. Simpler tests were so insensitive that by the time they showed abnormalities, the kidneys had often already lost more than half their filtering capacity.But now researchers have validated a faster, easier way to detect kidney trouble: a blood test that is factored into a formula that also uses age, gender, and race to estimate the kidney’s filtration rate, combined with a test to measure excreted protein. Testing is especially important if you’re age 60 or over have a personal history of diabetes, heart disease, high blood pressure, or any kidney disease or have a family history of kidney disease.An abnormal result, especially on the protein test, does not necessarily mean that you have kidney damage, since a bladder infection or other problems can increase protein excretion. If you have an abnormal result, get retested in a few months. A second abnormal finding indicates the need for further investigation.

Read Also: Grapes For Kidney Stones

How To Read Your Urine

Fortunately, no one still practices the medieval art of assessing health by tasting the urine. But changes in your urine or your urinary habits can provide warning signs of danger from disease or certain drugsor they may be harmless changes caused by food, supplements, or certain other drugs. This table can help you make that distinction. In general, consult your physician promptly about a urinary change if you have not consumed any of the benign substances listed below, or if you have any of the potentially harmful conditions or are taking any of the drugs listed. All but one of the potentially harmful medications affect the urine by impairing kidney function the exception is warfarin, which can redden the urine by causing bleeding.You may not have to contact your doctor quickly in two cases: You can usually treat dehydration simply by drinking more fluids if there are no other symptoms and you can usually wait a day or two before calling your doctor about a suspected urinary-tract infection, unless you have severe symptoms, such as back pain or fever.

Urinary signs or symptoms

Regular Use Of Pain Medicines Doesn’t Damage Kidneys

July 17, 2001 — Aspirin and similar pain medicines are such a part of everyday life — about a quarter of U.S. adults use them weekly — that most of us assume they’re perfectly safe. But for years, doctors have cautioned that regular use of these drugs can cause major damage to your kidneys and cause bleeding in the stomach.

A new study gives us one less thing to worry about: Moderate use of over-the-counter pain relievers isn’t likely to lead to kidney problems, the researchers found. However, two doctors who reviewed the study for WebMD believe overuse of pain medicines, particularly over a long period of time, may still be harmful.

The study in July 18 issue of the Journal of the American Medical Association looked at the use of nonprescription pain medicines such as aspirin, acetaminophen and non-steroidal anti-inflammatory drugs such as Motrin, Advil, or Aleve in more than 11,000 healthy men over a 14-year period.

They found no increase in kidney problems among men who took an average of three or four pills a week The study didn’t look at other possible side effects of these drugs such as harm to the liver or gastrointestinal bleeding.

People in the U.S. tend to drink too little water, and that puts additional stress on the kidneys, Avram says. “When you look at elderly people who drink only a small amount of water, and also take lots of pain medicines, that’s a set-up for disaster.”

Read Also: Reducose Weight Loss

Warning Disclaimer Use For Publication

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

What Clinical Trials Are Open

Is Aleve Hard On Kidneys - HealthyKidneyClub.com (2)

Clinical trials that are currently open and are recruiting can be viewed at www.ClinicalTrials.gov.

This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health. The NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.

The NIDDK would like to thank Jeffrey Fink, MD, MS, Chief, Division of General Internal Medicine, University of Maryland School of Medicine

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Could Diclofenac Gel Harm Your Kidneys

Q. I am especially sensitive to NSAIDs because of impaired kidney function. My doctor prescribed diclofenac gel for a muscle injury. Am I absorbing enough of this product to be harmful?

A. Nonsteroidal anti-inflammatory drugs like diclofenac, ibuprofen or naproxen can be hard on the kidneys. The official prescribing information for diclofenac warns that long-term administration could cause renal injury.

It is not clear whether you would absorb enough diclofenac from a topical gel to harm your kidneys. This is best determined by frequent monitoring. Ask your doctor to check your kidney function carefully.

Nsaids Are Bad For Your Blood Pressure

NSAIDs can cause high blood pressure. And if you have high blood pressure, they can make it worse. This increases your chances of having a heart attack or a stroke.

NSAIDs can also keep some blood pressure drugs from working right. NSAIDs can interfere with:

  • Diuretics, or water pills, such as Hydrodiuril . Diuretics remove excess water from the blood vessels.
  • ACE inhibitors, such as Prinivil and Zestril . ACE inhibitors are drugs that relax the blood vessels.
  • ARBs such as Cozaar . ARBs are another group of drugs that relax the blood vessels.

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Plan Ahead To Manage Pain Flu Or Other Illness

Almost everyone gets sick once in a while. Your doctor or pharmacist can help you plan ahead to keep your kidneys safe until you get well. Prepare in advance so you know what to do if you have pain or a fever, diarrhea, nausea, or vomiting, which can lead to dehydration.

Before you get sick, ask your health care provider or pharmacist the following questions

  • If I get sick, are there medicines I should not take while Im sick?
  • If I need to stop medicines when Im sick, when can I restart them?
  • What can I take or do to relieve a headache or other pain?
  • What can I take to relieve a fever?
  • If I have diarrhea or am vomiting, do I need to change how or when I take my blood pressure medicine?

Heart Attacks Strokes And Heart Failure:

How To REPAIR Your KIDNEYS Fast [in 10 minutes] – The 5 Things You Need To Know

There is growing recognition that NSAIDs can affect the cardiovascular system. Although most people do not understand heart failure very well , the outcomes can be disastrous. NSAIDs increase the risk of heart failure and if people have this condition NSAIDs can make it substantially worse .

An ongoing controversy in the medical community is whether some NSAIDs are more or less likely to cause heart attacks or strokes. Some studies suggest that naproxen may be a little less of a problem than some of the other pain relievers in this class. That said, the FDA has not given naproxen a green light in this matter. A study published in Current Vascular Pharmacology suggested the following:

The best safety profile related to MI was found for naproxen, while the worst safety profile, with excessively increased risk for stroke, MI and major bleeding, was for diclofenac. Naproxen showed higher risk for major bleeding than ibuprofen and the risk for stroke was slightly higher than ibuprofen. Regarding heart failure, ibuprofen presented the highest risk while the highest risk for AF was attributed to current use of diclofenac.

Here are some stories from readers to bring all this into focus. You can read more in the comment section below this article.

Rick was quite athletic and healthy until this happened:

Nana from Houston shared this:

Sherry in Waxhaw, NC points out that it took the FDA a long time to discover that NSAIDs could cause heart problems:

Recommended Reading: Fluid Backup In Kidneys

Symptoms Of Kidney Disease

Kidney disease is called a silent disease as there are often no warning signs. People may lose up to 90 per cent of their kidney function before getting any symptoms. The first signs of kidney disease may be general and can include:

  • high blood pressure
  • changes in the amount and number of times urine is passed
  • changes in the appearance of urine
  • blood in the urine
  • puffiness of the legs and ankles
  • pain in the kidney area
  • tiredness
  • have a family history of kidney failure
  • have a history of acute kidney injury
  • are of Aboriginal or Torres Strait Islander origin.

Can Analgesics Hurt Kidneys

Check with your doctor to be sure you can use these medicines safely, particularly if you have kidney disease. Heavy or long-term use of some of these medicines, such as ibuprofen, naproxen, and higher dose aspirin, can cause chronic kidney disease known as chronic interstitial nephritis. The warning labels on over-the-counter analgesics tell you not to use these medicines for more than l0 days for pain and more than three days for fever. If you have pain and/or fever for a longer time, you should see your doctor. The doctor can check for possible medical problems and advise you about what medications you should take.

If you have decreased kidney function, painkillers called NSAIDs and higher dose aspirin are not recommended. Even with normal kidney function, you should use analgesics:

  • Exactly as prescribed or as on the label
  • At the lowest dose possible
  • For the shortest period of time

Also Check: Do Multivitamins Cause Kidney Stones

FAQs

Is Aleve kidney friendly? ›

NSAIDS, or nonsteroidal anti-inflammatory drugs like ibuprofen (Advil, Motrin) and naproxen (Aleve), lead the list for drugs that cause kidney damage because of their widespread use.

Which is worse for your kidneys Aleve or Tylenol? ›

TYLENOL® does not affect kidney function the way that non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin (Bayer®), naproxen sodium (Aleve®), and ibuprofen (Advil®, MOTRIN® IB) can.

Which pain reliever is least harmful to the kidneys? ›

What analgesics are safe for people who have kidney disease? Acetaminophen remains the drug of choice for occasional use in patients with kidney disease because of bleeding complications that may occur when these patients use aspirin.

How long does it take for naproxen to cause kidney damage? ›

If these medications are used, doctors will monitor for side effects by checking blood tests more frequently. In one study, people who took NSAIDs showed double the risk of acute kidney injury within 30 days of starting the medication.

What pain reliever is hard on kidneys? ›

NSAIDs are bad for your heart and kidneys.

Long-term use of NSAIDs can make your body hold onto fluid. This can make the symptoms of heart failure, such as shortness of breath, swollen ankles, and a rapid or irregular heartbeat, worse. NSAIDs can also keep the kidneys from working well.

Is Aleve safer than Advil? ›

To sum it up, ibuprofen has a slightly lower risk of causing ulcers and gastrointestinal bleeding (bleeding from the esophagus and stomach) compared to naproxen. With any NSAID, it's best to take the lowest effective dose and avoid using it long term.

What over-the-counter medicine is good for kidneys? ›

Acetaminophen is the drug often recommended for occasional use in patients with kidney disease.

Can kidneys recover from NSAID damage? ›

Treatment. Renal function will recover in most patients after withdrawal of NSAID therapy. Steroids may aid recovery in patients with interstitial nephritis who do not improve after stopping NSAID therapy.

How do you improve kidney function? ›

What can I do to keep my kidneys healthy?
  1. Make healthy food choices. ...
  2. Make physical activity part of your routine. ...
  3. Aim for a healthy weight. ...
  4. Get enough sleep. ...
  5. Stop smoking. ...
  6. Limit alcohol intake link. ...
  7. Explore stress-reducing activities. ...
  8. Manage diabetes, high blood pressure, and heart disease.

What is the safest anti-inflammatory medication? ›

Experts say that taking NSAIDs for a short time at the lowest effective dose is generally safe.
...
This class of medications includes:
  • Aspirin (full dose)
  • Celecoxib (used in Celebrex)
  • Diclofenac (used in Votaren)
  • Ibuprofen (used in Advil or Motrin)
  • Naproxen (used in Aleve)
19 Nov 2021

How much Aleve can I take? ›

Adults—550 milligrams (mg) for the first dose, then 550 mg every 12 hours or 275 mg every 6 to 8 hours as needed. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1375 mg per day. Children—Use and dose must be determined by your doctor.

What can I take instead of ibuprofen for inflammation? ›

Naproxen and aspirin are two other common over-the-counter pain relievers. Reeder describes the uses, benefits and potential problems with these as well: Naproxen. Another anti-inflammatory drug, which works much like ibuprofen.

Does Aleve raise blood pressure? ›

NSAIDs can also raise your risk for heart attack or stroke, especially in higher doses. Common NSAIDs that can raise blood pressure include: Ibuprofen (Advil, Motrin) Naproxen (Aleve, Naprosyn)

What are the symptoms of poor kidney function? ›

Depending on how severe it is, loss of kidney function can cause:
  • Nausea.
  • Vomiting.
  • Loss of appetite.
  • Fatigue and weakness.
  • Sleep problems.
  • Urinating more or less.
  • Decreased mental sharpness.
  • Muscle cramps.
3 Sept 2021

Can you reverse kidney damage from ibuprofen? ›

Generally, the renal failure with NSAIDs is acute and reversible, though analgesic nephropathy with papillary necrosis and chronic renal failure are reported.

Is Tylenol or ibuprofen worse for your kidneys? ›

Ibuprofen is harder on the kidneys than acetaminophen. Acetaminophen doesn't have the same effect on the COX pathway as ibuprofen. So kidney damage is much more rare. Kidney issues are typically only reported when a person has taken too much acetaminophen.

Is Advil hard on kidneys? ›

Some common medications like ibuprofen and naproxen are known to even cause kidney problems.

Can I take Tylenol every night before bed? ›

Acetaminophen helps to reduce fever and/or mild to moderate pain (such as headache, backache, aches/pains due to muscle strain, cold, or flu). The antihistamine in this product may cause drowsiness, so it can also be used as a nighttime sleep aid.

Is it OK to take Aleve every day? ›

Key Points in Making the NSAID Decision

Examples include aspirin, Advil, Aleve, Motrin, and prescription drugs like Celebrex. You should never take any over-the-counter medicine regularly without discussing it with your doctor. Most over-the-counter painkillers should not be used for more than 10 days.

Which is safest Tylenol or Aleve? ›

Both Aleve® and TYLENOL® temporarily reduce fever and relieve minor aches and pains. TYLENOL®, which contains acetaminophen, may be a more appropriate option than Aleve®, which contains naproxen sodium an NSAID, for those with heart or kidney disease, high blood pressure, or stomach problems.

What are the risks of taking Aleve? ›

Side Effects
  • Upset stomach, nausea, heartburn, headache, drowsiness, or dizziness may occur. ...
  • If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. ...
  • This medication may raise your blood pressure.

What medications should you avoid if you have kidney disease? ›

What medications to avoid with kidney disease
  • Pain medications also known as nonsteroidal anti-inflammatory drugs (NSAIDs) ...
  • Proton pump inhibitors (PPIs) ...
  • Cholesterol medications (statins) ...
  • Antibiotic medications. ...
  • Diabetes medications. ...
  • Antacids. ...
  • Herbal supplements and vitamins. ...
  • Contrast dye.

What medications can damage your kidneys? ›

What Meds Might Hurt My Kidneys?
  • Antibiotics.
  • Diuretics.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Proton Pump Inhibitors (PPIs)
  • Supplements.
  • Laxatives.
  • If You Have Kidney Disease, Other Medications Can Be Harmful.
27 Jan 2022

Can kidney function affect bowel movements? ›

Abstract. Constipation is highly prevalent in patients with chronic kidney disease (CKD) and is primarily characterized by decreased intestinal motility. This chronic disorder affects the quality of life of patients.

How long does it take for kidneys to recover from NSAIDs? ›

After cessation of NSAID treatment and rehydration, all patients recovered completely with a normalised creatinine level after 3 to 9 days.

How long does it take for NSAIDs to leave your system? ›

Official answer. After taking your last dose of naproxen it should be out of your system within 93.5 hours. Naproxen has an elimination half life of 12 to 17 hours. This is the time it takes for your body to reduce plasma drug levels by half.

How long does it take ibuprofen to damage kidneys? ›

The average onset time of APAP-related kidney injury was 32.74 days, which was about a quarter of that of ibuprofen-related kidney injury (115.82 days).

What food heals your kidneys? ›

20 Healthful Foods for Fighting Kidney Disease
  • Blueberries. Blueberries and other dark berries like strawberries and raspberries are among the best sources of antioxidants to help protect your kidneys. ...
  • Cauliflower. ...
  • Olive Oil. ...
  • Garlic. ...
  • Bell Peppers. ...
  • Cabbage. ...
  • Skinless Chicken. ...
  • Arugula.
4 Nov 2019

Can kidney function ever improve? ›

Can anything else impact my GFR? It is possible to slow the progression of kidney disease by taking good care of yourself by following a healthy diet and exercising. However, for some people, their kidney disease gets worse despite their best efforts at a healthy lifestyle.

What is a normal GFR for a 70 year old? ›

However, we know that GFR physiologically decreases with age, and in adults older than 70 years, values below 60 mL/min/1.73 m2 could be considered normal.

What is the safest NSAID to take long term? ›

In contrast, naproxen seems to have the safest cardiovascular profile and is the best treatment option in patients with high cardiovascular risk.

What can you take instead of naproxen? ›

Diclofenac sodium and aceclofenac are similar in efficacy to naproxen. Etodolac is comparable in efficacy to naproxen; it is licensed for symptomatic relief of osteoarthritis and rheumatoid arthritis.

What can I take instead of NSAIDs? ›

Acetaminophen is a safe alternative to NSAIDs for people who are allergic or hypersensitive to ibuprofen or other NSAIDs. In addition, certain supplements can help provide relief from inflammation and pain. Common alternatives to NSAIDs include arnica, curcumin, and bromelain.

Can you take 4 Aleve a day? ›

Take one tablet, caplet, gelcap or liquid gel every 8 to 12 hours while symptoms last. For the first dose, you may take 2 pills within the first hour. Do not exceed more than 2 tablets, caplets, gelcaps or liquid gels in 12 hours, and do not exceed 3 tablets, caplets, gelcaps or liquid gels in 24 hours.

Can I take 2 Aleve? ›

You may take two pills within the first hour for the first dose. Do not take more than two tablets, caplets, gelcaps, or liquid gels in a 12-hour period, and no more than three tablets, caplets, gelcaps, or liquid gels in a 24-hour period.

How many Aleve 220 mg can I take? ›

adults and children 12 years and older: take 1 tablet every 8 to 12 hours while symptoms last. for the first dose you may take 2 tablets within the first hour. do not exceed 2 tablets in any 8- to 12-hour period.

What is the most natural painkiller? ›

Endorphins are the natural pain killers produced by your body. They work by binding to the opioid receptors in your brain to block the perception of pain.

Is long term use of Aleve harmful? ›

Side effects from long-term use

This extra work can cause pressure on your cardiovascular system and can sometimes lead to a heart attack or stroke. These risks are even greater at higher dosages, even if you don't have any heart conditions or risk of heart disease.

What anti-inflammatory is not an NSAID? ›

Acetaminophen (Tylenol) is known as a non-aspirin pain reliever. It is NOT an NSAID, which is described below. Acetaminophen relieves fever and headaches, and other common aches and pains. It does not relieve inflammation.

Is naproxen safe for kidneys? ›

Are NSAIDs safe to take if you have kidney disease? NSAIDs are usually safe for occasional use when taken as directed. However, if your doctor has told you that you have low kidney function, NSAIDs might not be right for you. These medications should only be used under a doctor's care by patients with kidney disease.

Is Tylenol or ibuprofen worse for your kidneys? ›

Ibuprofen is harder on the kidneys than acetaminophen. Acetaminophen doesn't have the same effect on the COX pathway as ibuprofen. So kidney damage is much more rare. Kidney issues are typically only reported when a person has taken too much acetaminophen.

Is Tylenol hard on your kidneys? ›

Is Tylenol bad for my kidneys? No. In fact, Tylenol is preferred over other OTC pain relievers if you have kidney problems.

What is the safest anti-inflammatory medication? ›

Experts say that taking NSAIDs for a short time at the lowest effective dose is generally safe.
...
This class of medications includes:
  • Aspirin (full dose)
  • Celecoxib (used in Celebrex)
  • Diclofenac (used in Votaren)
  • Ibuprofen (used in Advil or Motrin)
  • Naproxen (used in Aleve)
19 Nov 2021

Can kidneys recover from NSAID damage? ›

Treatment. Renal function will recover in most patients after withdrawal of NSAID therapy. Steroids may aid recovery in patients with interstitial nephritis who do not improve after stopping NSAID therapy.

Is it safe to take Aleve every day for arthritis? ›

Key Points in Making the NSAID Decision

Examples include aspirin, Advil, Aleve, Motrin, and prescription drugs like Celebrex. You should never take any over-the-counter medicine regularly without discussing it with your doctor. Most over-the-counter painkillers should not be used for more than 10 days.

What pain reliever is not a NSAID? ›

Acetaminophen, such as Tylenol, is a widely available alternative to NSAIDs that targets pain rather than inflammation.

What medications help kidney function? ›

ACE inhibitors and ARBs are two types of blood pressure medicine that may slow the loss of kidney function and delay kidney failure.

What can I take instead of ibuprofen for inflammation? ›

Naproxen and aspirin are two other common over-the-counter pain relievers. Reeder describes the uses, benefits and potential problems with these as well: Naproxen. Another anti-inflammatory drug, which works much like ibuprofen.

What pain meds affect the kidneys? ›

Painkillers that combine 2 or more medicines (such as, aspirin and acetaminophen together) with caffeine or codeine are the most likely to harm the kidneys.
...
Examples include:
  • Aspirin.
  • Acetaminophen.
  • Ibuprofen.
  • Naproxen sodium.

What is a good substitute for Tylenol? ›

At the drugstore, the most common alternatives to acetaminophen are ibuprofen (brand names Advil and Motrin) and naproxen (brand names Aleve, Naprosyn, and Anaprox). Both of these are part of a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).

What are the symptoms of poor kidney function? ›

Depending on how severe it is, loss of kidney function can cause:
  • Nausea.
  • Vomiting.
  • Loss of appetite.
  • Fatigue and weakness.
  • Sleep problems.
  • Urinating more or less.
  • Decreased mental sharpness.
  • Muscle cramps.
3 Sept 2021

What is the safest NSAID to take long term? ›

In contrast, naproxen seems to have the safest cardiovascular profile and is the best treatment option in patients with high cardiovascular risk.

What can you take instead of naproxen? ›

Diclofenac sodium and aceclofenac are similar in efficacy to naproxen. Etodolac is comparable in efficacy to naproxen; it is licensed for symptomatic relief of osteoarthritis and rheumatoid arthritis.

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Last Updated: 11/04/2022

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Name: Kerri Lueilwitz

Birthday: 1992-10-31

Address: Suite 878 3699 Chantelle Roads, Colebury, NC 68599

Phone: +6111989609516

Job: Chief Farming Manager

Hobby: Mycology, Stone skipping, Dowsing, Whittling, Taxidermy, Sand art, Roller skating

Introduction: My name is Kerri Lueilwitz, I am a courageous, gentle, quaint, thankful, outstanding, brave, vast person who loves writing and wants to share my knowledge and understanding with you.