By StoryStudio July 27, 2022 2:29 pm
(BPT) – Sponsored by Janssen
Imagine finding simple tasks, such as getting out of bed, dressing yourself or turning a faucet on and off, difficult to do because they’re too painful.1That’s what a typical day can feel like for people living with active psoriatic arthritis (PsA). About 1.5 million Americans are living with PsA, and although patients may experience symptoms differently, the condition can often interfere with basic daily activities.1,2
Active PsA is a chronic condition that occurs when your body’s immune system attacks healthy cells and tissue, which causes inflammation in the joints as well as overproduction of skin cells.3Common symptoms of active PsA include joint stiffness, pain and swelling.4Some patients with active PsA can also experience fatigue, which is an underestimated and underreported concern that can interfere with daily life.4-6
PsA symptoms can vary and differ in severity from patient to patient, so it’s critical for healthcare providers and patients to have an open dialogue to build a personalized management plan together.4A PsA management plan may incorporate lifestyle changes as well as medication potentially to help address the disease symptoms.
“The symptoms of active psoriatic arthritis may be hard to describe or feel invisible at times, but that doesn’t make them any less real,” said Soumya D. Chakravarty, MD, PhD, Senior Director, Strategic Lead, Rheumatology Therapeutic Area at Janssen. “PsA can have debilitating effects on the lives of patients. It’s important for patients to speak about symptoms with their rheumatologist because there are strategies they can implement to help see improvement.”
Here are some top tips for managing symptoms of PsA:
Consider a Healthy Diet
While there isn’t a specific diet for PsA, research shows that certain foods can help reduce inflammation in the body, which contributes to the disease.7Consider incorporating more anti-inflammatory foods, such as fruits, vegetables, beans, whole grains and healthy fats like fish and avocado, while reducing foods like fatty red meats, dairy, refined sugars and processed foods.7,8
Think About Finding a Workout That Feels Good
Exercise while living with active PsA can feel daunting, but physical activity has many benefits, including helping to maintain a healthy weight, taking extra pressure off painful joints, keeping joints flexible and increasing endorphins, which can provide an energy boost.8,9Make sure to speak with your healthcare provider or a physical therapist about a workout routine that is right for you. As a general guide, try to target 30 minutes of movement each day if you’re able and consider lower impact workouts.8
Lean On a Support System
For people living with PsA, the disease can have an impact beyond just physical symptoms.10Connecting with other patients who understand what you’re experiencing, whether in a support group or an online community, can help if you’re feeling overwhelmed, misunderstood or isolated.10
Start a Dialogue With Your Healthcare Provider About Treatment Options
In addition to physical tests to assess the severity of your PsA, rheumatologists are also building treatment plans based on outcomes that are more personally significant to patients.6“It’s important to speak openly with your rheumatologist because there are treatments that may help improve PsA symptoms,” said Dr. Chakravarty.
Be sure to describe your symptoms — such as joint pain, stiffness and swelling — with specific details about how they impact your daily activities.Also, let your rheumatologist know if you are experiencing fatigue from your active PsA. This information will help them develop an individualized treatment plan that is right for you, which may include a biologic therapy, such as TREMFYA®(guselkumab) — a prescription medicine used to treat adults with active PsA. Talk to your doctor to see if TREMFYA®is appropriate for you. TREMFYA®is the first FDA-approved medication of its kind to selectively block interleukin 23 (IL-23), one of the key proteins thought to be responsible for symptoms of PsA. TREMFYA®can help reduce the joint pain, stiffness, and swelling that make everyday tasks harder to do. In two medical studies, more than half of patients treated with TREMFYA®had at least a 20% improvement in joint pain, stiffness, and swelling at 24 weeks. Furthermore, at 24 weeks, people taking TREMFYA®showed an overall improvement in their ability to perform daily activities such as getting dressed, eating and walking. Some patients also reported improvement in fatigue as measured by the Functional Assessment of Chronic Illness Therapy – Fatigue (FACIT-F), a questionnaire to measure self-reported tiredness, weakness, and difficulty conducting usual activities due to fatigue.
TREMFYA®is not for everyone; only your doctor can decide if it’s right for you. Do not use if you are allergic to TREMFYA®. TREMFYA®is a prescription medicine that may cause serious side effects, including serious allergic reactions and infections. It affects your immune system and may increase your risk of infections and lower your ability to fight them. Patients should be instructed to seek medical advice if signs and symptoms of clinically important chronic or acute infection occur. Patients should also be evaluated for tuberculosis before being treated with TREMFYA®. Please read the Important Safety Information and the Medication Guide for TREMFYA®available atwww.tremfya.comto learn more about these and other risks for TREMFYA®. Discuss any questions you have with your doctor.
Coping with PsA can be overwhelming at times, but as difficult as it may be, don’t get discouraged. There’s no one-size-fits-all approach to PsA management and it’s important to remember you have options. There are various steps you can take with your rheumatologist to help alleviate symptoms and better manage the disease.
WHAT IS TREMFYA®? (guselkumab)
TREMFYA®is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).
TREMFYA®is a prescription medicine used to treat adults with active psoriatic arthritis.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about TREMFYA®?
TREMFYA®is a prescription medicine that may cause serious side effects, including:
- Serious Allergic Reactions.Stop using TREMFYA®and get emergency medical help right away if you develop any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth, tongue or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- Infections.TREMFYA®may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with TREMFYA®and may treat you for TB before you begin treatment with TREMFYA®if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with TREMFYA®.
Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- muscle aches
- weight loss
- warm, red, or painful skin or sores on your body different from your psoriasis
- diarrhea or stomach pain
- shortness of breath
- blood in your phlegm (mucus)
- burning when you urinate or urinating more often than normal
Do not take TREMFYA®if you have had a serious allergic reaction to guselkumab or any of the ingredients in TREMFYA®.
Before using TREMFYA®, tell your healthcare provider about all of your medical conditions, including if you:
- have any of the conditions or symptoms listed in the section“What is the most important information I should know about TREMFYA®?”
- have an infection that does not go away or that keeps coming back.
- have TB or have been in close contact with someone with TB.
- have recently received or are scheduled to receive an immunization (vaccine). You should avoid receiving live vaccines during treatment with TREMFYA®.
- are pregnant or plan to become pregnant. It is not known if TREMFYA®can harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if TREMFYA®passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of TREMFYA®?
TREMFYA®may cause serious side effects. See “What is the most important information I should know about TREMFYA®?”
The most common side effects of TREMFYA®include:upper respiratory infections, headache, injection site reactions, joint pain (arthralgia), diarrhea, stomach flu (gastroenteritis), fungal skin infections, herpes simplex infections, and bronchitis.
These are not all the possible side effects of TREMFYA®. Call your doctor for medical advice about side effects.
Use TREMFYA®exactly as your healthcare provider tells you to use it.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visitwww.fda.gov/medwatch, or call 1-800-FDA-1088.
- Kavanaugh, A., Helliwell, P., & Ritchlin, C. T. Psoriatic Arthritis and Burden of Disease: Patient Perspectives from the Population-Based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) Survey.Rheumatology and therapy,3(1), 91–102. (2016). Accessed April 1, 2022.https://doi.org/10.1007/s40744-016-0029-z
- Johns Hopkins. Psoriatic Arthritis. Accessed April 1, 2022.https://www.hopkinsarthritis.org/arthritis-info/psoriatic-arthritis/#:%7E:text=What%20is%20Psoriatic%20Arthritis%3F,may%20also%20affect%20the%20spine.
- Mayo Clinic. Psoriatic Arthritis. Accessed April 1, 2022.https://www.mayoclinic.org/diseases-conditions/psoriatic-arthritis/symptoms-causes/syc-20354076.
- National Psoriasis Foundation. About Psoriatic Arthritis. Accessed June 1, 2022.https://www.psoriasis.org/about-psoriatic-arthritis/.
- CreakyJoints. What Does Psoriatic Arthritis Fatigue Really Feel Like? Accessed June 1, 2022.https://creakyjoints.org/about-arthritis/psoriatic-arthritis/psa-symptoms/what-psoriatic-arthritis-fatigue-feels-like/
- Nowell, W.B., Gavigan, K., Kannowski, C.L. et al. Which Patient-Reported Outcomes Do Rheumatology Patients Find Important to Track Digitally? A Real-World Longitudinal Study in ArthritisPower.Arthritis Res Ther23,53 (2021).https://doi.org/10.1186/s13075-021-02430-0
- National Psoriasis Foundation. What’s the Deal with the Anti-Inflammatory Diet? Accessed June 1, 2022.https://www.psoriasis.org/advance/whats-the-deal-with-the-anti-inflammatory-diet/.
- Arthritis Foundation. Psoriatic Arthritis Self-Care Tips. Accessed April 1, 2022.https://www.arthritis.org/diseases/more-about/psoriatic-arthritis–self-care-tips.
- Creaky Joints. Psoriatic Arthritis Fatigue: 20+ Daily Routine Changes to Improve Energy. Accessed April 1, 2022.https://creakyjoints.org/about-arthritis/psoriatic-arthritis/psa-healthy-living/psoriatic-arthritis-fatigue-routine-changes/.
- CreakyJoints. Psoriatic Arthritis and Mental Health: Link to Depression, Anxiety, Fatigue. Accessed June 1, 2022.https://creakyjoints.org/about-arthritis/psoriatic-arthritis/psa-treatment/psoriatic-arthritis-mental-health/.
This sponsored article is presented by Brandpoint.
NSAIDs. Nonsteroidal anti-inflammatory drugs (NSAIDs) can relieve pain and reduce inflammation for people with mild psoriatic arthritis. NSAIDs available without a prescription include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve). Stronger NSAIDs are available by prescription.
Disease-modifying antirheumatic drugs (DMARDs).
DMARDs, such as methotrexate (Trexall), leflunomide (Arava), and sulfasalazine (Azulfidine), work to slow the progression of psoriatic arthritis. While this can help to prevent permanent joint damage, these drugs have many potential side effects.
Saturated fats, sugar, alcohol, and simple carbohydrates can add pounds, cause inflammation, and trigger psoriatic arthritis flares. Try to avoid foods such as: Processed meats like hot dogs, sausages, and bacon. Sugary drinks.
Getting psoriatic arthritis (PsA) under control and achieving remission is possible with currently available medications. Psoriatic arthritis is a form of inflammatory arthritis that affects both skin and joints. It is treated with conventional disease-modifying antirheumatic drugs (DMARDs) and biologics.
- Ease arthritis symptoms.
- Improve how you move.
- Get stronger and more flexible.
- Keep your weight healthy, which takes pressure off your joints.
- Help your heart.
- Boost your mood.
- Give yourself more energy.
According to the report's authors, Maryland scored the highest marks for the best state to live in with Arthritis because it has a very high concentration of rheumatologists and a low rate of residents without health insurance.
The best endurance exercises for people who have psoriatic arthritis are walking, swimming, and biking, Lindsey says. In a study published in 2021 in the journal Rheumatology and Therapy, walking, combined with continuous health education, reduced the incidence of flares. If you're able, running is fine too.
Psoriatic arthritis does not usually affect a person's life expectancy and it is not life-threatening. However, it can increase the risk for other conditions (co-morbidities) that can, such as cardiovascular disease, fatty liver disease, high blood pressure, and diabetes.
It typically takes more than 3 months to receive a decision, but it can take up to 2 years in some cases. You can begin the process by filling out an online application, calling Social Security, or visiting your local Social Security office.
Guselkumab (Tremfya) is the newest biologic drug approved to treat PsA. It's the first biologic to target the immune system protein IL-23. Another IL-23 drug called risankizumab (Skyrizi) is already approved to treat psoriasis and PsA. About a dozen biologics are FDA-approved for psoriatic arthritis.
Mikulik says. Instead, drink green tea: It contains compounds that may block the pro-inflammatory cytokine interleukin-1, keeping it from damaging cartilage in the joints, according to the Arthritis Foundation.
Although genetics appear to play a role in its development, certain environmental triggers can also give rise to PsA, including exposure to smoke, stress, and cold weather. Risk factors for PsA include age and family history.
A study published in 2015 in the journal PLoS One found that the overall pain, joint pain, and fatigue reported by psoriatic arthritis patients was significantly greater than that reported by people with rheumatoid arthritis.
Psoriatic arthritis (PsA) is a complicated condition that can present very differently in different people. Currently, there is no cure for this condition.
Psoriatic arthritis involves inflammation, pain, and swelling in the joints. Some natural treatment options — including stress reduction, exercise, capsaicin, and oatmeal — may help.
- Decrease pain and stiffness. For occasional discomfort, Fields says, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen can be beneficial. ...
- Incorporate arthritis-friendly exercise. ...
- Reduce stress. ...
- Get extra rest. ...
- Consider using assistive devices.
Research suggests that some people with psoriatic arthritis have a vitamin D deficiency. Vitamin D is especially important for bone health. Take steps to increase your vitamin D intake through sun exposure and food sources like milk and fortified juice and cereals. Your doctor may recommend a vitamin D supplement.
Foods like fatty red meats, dairy, refined sugars, processed foods, and possibly vegetables like potatoes, tomatoes, and eggplants (you might hear them called nightshades) may all cause inflammation. Avoid them and choose fish, like mackerel, tuna, and salmon, which have omega-3 fatty acids.
- Omega-3 fatty acids are a type of polyunsaturated fatty acid (PUFA). ...
- Fill your shopping basket with fresh fruits, vegetables, nuts, and spices. ...
- The best food sources of antioxidants include:
If your psoriatic arthritis affects your feet and/or hands, practice self-care to help relieve symptoms and prevent injuries that may lead to flares: Apply cold packs to your feet and hands to relieve swelling and aching.
The takeaway. The best way to manage PsA symptoms and prevent complications is with medication prescribed by your doctor. You may also want to consider making changes to your diet, for instance, the beverages you drink. The best drinks for PsA include green tea, coffee, and plain water.
Summary. Pernicious anemia, which is caused by a vitamin B12 deficiency, may occur more often in people with other autoimmune diseases, including psoriatic arthritis. The condition needs to be treated with vitamin B12 to prevent serious complications.